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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARHGAP25 All Species: 22.73
Human Site: Y583 Identified Species: 71.43
UniProt: P42331 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P42331 NP_001007232.1 645 73435 Y583 K N L E K E N Y D V W A K V V
Chimpanzee Pan troglodytes XP_001135470 646 73502 Y584 K N L E K E N Y D V W A K V V
Rhesus Macaque Macaca mulatta XP_001095743 646 73554 Y584 K N L E K E N Y D V W A K V V
Dog Lupus familis XP_538527 713 78537 Y651 E N L E K E N Y D V W A K V V
Cat Felis silvestris
Mouse Mus musculus Q8BYW1 648 73364 Y584 K N L E K E N Y D V W A K V V
Rat Rattus norvegicus Q5U2Z7 748 84125 L674 K S L E Q R N L T L E T E M L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026054 650 73116 Y587 K S L E K E N Y D V W A K V V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_690970 695 77458 A628 R R L E E S S A A L H K Q M E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.1 69.5 N.A. 86.8 38 N.A. N.A. 61.8 N.A. 38.8 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 98.4 76.4 N.A. 91.3 54.4 N.A. N.A. 73.8 N.A. 58.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 100 26.6 N.A. N.A. 93.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 66.6 N.A. N.A. 100 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 13 13 0 0 75 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 75 0 0 0 0 0 0 % D
% Glu: 13 0 0 100 13 75 0 0 0 0 13 0 13 0 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 75 0 0 0 75 0 0 0 0 0 0 13 75 0 0 % K
% Leu: 0 0 100 0 0 0 0 13 0 25 0 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % M
% Asn: 0 63 0 0 0 0 88 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 13 0 0 0 0 0 0 0 13 0 0 % Q
% Arg: 13 13 0 0 0 13 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 25 0 0 0 13 13 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 13 0 0 13 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 75 0 0 0 75 75 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _